Gene description for VTN
Gene name vitronectin
Gene symbol VTN
Other names/aliases V75
VN
VNT
Species Homo sapiens
 Experiment description of studies that identified VTN in Leukemia cells

1
Experiment ID607
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleLeukemia cells
Sample nameSR
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -

2
Experiment ID1248
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 24939845   
OrganismHomo sapiens
Experiment descriptionHuman T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.
AuthorsJaworski E, Narayanan A, Van Duyne R, Shabbeer-Meyering S, Iordanskiy S, Saifuddin M, Das R, Afonso PV, Sampey GC, Chung M, Popratiloff A, Shrestha B, Sehgal M, Jain P, Vertes A, Mahieux R, Kashanchi F.
Journal name J Biol Chem.
Publication year2014
SampleLeukemia cells
Sample nameCEM - uninfected
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV140028: EV-METRIC:33%

3
Experiment ID1249
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 24939845   
OrganismHomo sapiens
Experiment descriptionHuman T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.
AuthorsJaworski E, Narayanan A, Van Duyne R, Shabbeer-Meyering S, Iordanskiy S, Saifuddin M, Das R, Afonso PV, Sampey GC, Chung M, Popratiloff A, Shrestha B, Sehgal M, Jain P, Vertes A, Mahieux R, Kashanchi F.
Journal name J Biol Chem.
Publication year2014
SampleLeukemia cells
Sample nameC81 - HTLV-1 infected
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV140028: EV-METRIC:33%

4
Experiment ID1250
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 24939845   
OrganismHomo sapiens
Experiment descriptionHuman T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.
AuthorsJaworski E, Narayanan A, Van Duyne R, Shabbeer-Meyering S, Iordanskiy S, Saifuddin M, Das R, Afonso PV, Sampey GC, Chung M, Popratiloff A, Shrestha B, Sehgal M, Jain P, Vertes A, Mahieux R, Kashanchi F.
Journal name J Biol Chem.
Publication year2014
SampleLeukemia cells
Sample nameMT2 - HTLV-1 infected
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV140028: EV-METRIC:33%

5
Experiment ID1251
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 24939845   
OrganismHomo sapiens
Experiment descriptionHuman T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein.
AuthorsJaworski E, Narayanan A, Van Duyne R, Shabbeer-Meyering S, Iordanskiy S, Saifuddin M, Das R, Afonso PV, Sampey GC, Chung M, Popratiloff A, Shrestha B, Sehgal M, Jain P, Vertes A, Mahieux R, Kashanchi F.
Journal name J Biol Chem.
Publication year2014
SampleLeukemia cells
Sample nameED-40515 -HTLV-1 infected
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV140028: EV-METRIC:33%

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